Campione has a considerable amount of economic and administrative integration with Switzerland. Because of its particular status, legal tender in the town is the Swiss Franc but the Euro is widely accepted; Italian citizens residing in Campione must abide by Swiss law regarding customs duties.

Presently, car plates are not Italian, but Swiss; similarly, the telephone system is almost entirely operated by Swisscom, meaning that calls from Italy (with very few exceptions such as calling the city hall) require the international dialing code for Switzerland (0041) and the Ticino area code: (91). Mail may be sent using either a Swiss postal code or an Italian one using Switzerland or Italy as destination country respectively.